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Neurofibromatosis type 1 (NF1) in children, as in adults, does not directly require adaptation of the vaccination schedule: there are no additional or contraindicated vaccines.

The possible indication for additional vaccines,other than those of the conventional vaccination schedule,for patients with NF1, similarly to people with chronic diseases, depends on the following factors:

  • Possible intake of immunosuppressive or immunomodulatory drugs.
  • Possible complications of NF1: malignant tumours of nerve sheath, other cancers.
  • Possibly associated comorbidities independent of NF1: cardiac, respiratory, renal failure, hemopathies...

"" website, attached to the Ministry of Health, also provides clear, precise, and appropriate information on vaccination in general. It also provides answers to questions about vaccination against SARS-CoV-2 (COVID-19).

Finally, the Weekly Epidemiological Bulletin (Bulletin Épidémiologique Hebdomadaire, BEH), a peer-reviewed journal edited by the Public Health in France, publishes articles suggested by all public health actors. Each year, it publishes the classic vaccination schedule adapted to possible chronic pathologies. Its access is freely available online. Do not hesitate to consult it regularly.